Understanding what works to improve diabetes outcomes

Study title: A systematic review of pharmacological and non-pharmacological
interventions for improving diabetes outcomes in people with severe mental illness (SMI)

Study duration: November 2014 to March 2016

This study aims to understand how effective drug treatments and behavioural programmes are for improving diabetes outcomes in people with SMI, by reviewing the existing evidence.

Building on other published reviews, which show that both approaches can lead to weight loss for this patient population, this systematic review draws together studies that measure fasting glucose and HbA1c, which are the main outcomes used to diagnose diabetes, and to measure diabetes control in people who have the illness.

We have identified 53 studies to include in our review. 13 are behavioural interventions, 39 are pharmacological interventions, and 1 study combines both approaches. We are currently writing the findings from the review for publication.

Our study protocol is published on Prospero. Please click on the link below to access this: